Active Pharmaceutical Ingredients (API) & Intermediates

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Product name
CAS
Formula
CAS24359-22-6
FormulaC23H27NO5S
Synonym-
Assay/PurityTypically NLT 98%
CAS139110-80-8
FormulaC17H13ClN4
SynonymGANA GNA Modified sialic acid Zanamavir ZMR, (2R,3R,4S)-4-[(diaminomethylidene)amino]-3-acetamido-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
Molecular weight332.3098
Assay/PurityTypically NLT 98%
CAS302-79-4
FormulaC17H12Cl2N4
SynonymAll Trans Retinoic Acid All Trans-Retinoic Acid ATRA beta-Retinoic Acid Retionic Acid, 3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-en-1-yl)nona-2,4,6,8-tetraenoic acid, Retinoic acid
Molecular weight300.4351
Assay/PurityTypically NLT 98%
CAS4070-80-8
FormulaC22H39NaO4
SynonymSodium stearoyl fumarate, Sodium octadecyl fumarate
Saponification number142-146
Practically Insolublein water
Slightly Solublein methanol
Molecular weight390.54
Assay/PurityTypically NLT 98%
CAS9000-55-9
SynonymPODOPHYLIUM RESIN, PODOPHYLLUM RESIN, PODOPHYLLIN, PODOPHYLLIN EX PODOPHYLLUM HEXANNDRUM, PODOPHYLLIN EX PODOPHYLLUM PELTATUM, podofillina, podophyllinfrompodophyllumpeltatum, podophyllum
Molecular weight1693.65
Assay/PurityTypically NLT 98%
CAS82410-32-0
FormulaC15H21N3O3S
SynonymGA2 Ganciclovir Sodium, 2-amino-9-{[(1,3-dihydroxypropan-2-yl)oxy]methyl}-6,9-dihydro-3H-purin-6-one
Molecular weight255.2306
Assay/PurityTypically NLT 98%
CAS7727-43-7
FormulaBaSO4
SynonymBarite Powder, Sulfuric acid, barium salt (1:1)
Density4.25-4.5
Practically Insolublein water, dilute acids, alcohol
Chloride< 0.001%
Assay> 97.0%
Acidity< 0.01%
Water-soluble salts< 0.02%
Phosphate< 0.001%
Iron< 0.001%
Heavy Metals< 0.001%
Melting Point1580 c
Odorwh. or ylsh. fine powd. free from grittiness, odorless, tasteless
Refractive Index1.64
Molecular weight233.40
Solubilityconc. sulfuric acid
CAS1309-42-8
FormulaMg(OH)2
SynonymBrucite, Magnesia magma, Magnesium hydrate, Milk of magnesia, Magnesium hydroxide (Mg(OH)2), Magnesium hydroxide
Density2.36
Melting Point350 c (dec.)
Particle Size: Passes 325 mesh (wet Sieve)HD7 - 95.0% min
Particle Size: Passes 325 mesh (wet Sieve)HD9 - 95.0% min
Particle Size: Passes 325 mesh (wet Sieve)HD12 - 90.0% min
Tapped Density (1000 taps)HD12 - 1.01 - 1.25 g/cc
Calcium as Ca1.50% max
Heavy Metals, as Pb20 ppm max
Bulk Density (untapped)HD7 - 0.40 - 0.65 g/cc
Magnesium Hydroxide as Mg(OH)295.0 - 100.5%
IdentificationPositive test for Magnesium
Microbial enumeration testPasses test
Loss on Ignition30.0 - 33.0% max
Loss on Drying2.00% max
Free Alkali2 ml
Soluble Salts2.00% max
Carbonatesto pass effervascence test
Lead as Pb1.5 ppm max
Bulk Density (untapped)HD5 - 0.25 - 0.55 g/cc
Bulk Density (untapped)HD9 - 0.60 - 0.80 g/cc
Bulk Density (untapped)HD12 - max 1.10 g/cc
Tapped Density (1000 taps)HD5 - 0.40 - 0.60 g/cc
Tapped Density (1000 taps)HD7 - 0.61 - 0.80 g/cc
Tapped Density (1000 taps)HD9 - 0.81 - 1.00 g/cc
Particle Size: Passes 325 mesh (wet Sieve)HD5 - 95.0% min
Odorodorless
Molecular weight58.33
Colorwhite amorphous powder or colorless hexagonal crystal
Solubilitysoln. of ammonium salts and dilute acids
CAS90604-80-1
FormulaAl4Zr(OH)12Cl4 Gly x nH2O
SynonymAluminium Zirconium Tetrachlorohydrex Gly
Aluminumca. 15%
Heavy metals (as Pb)20 ppm max.
pH (15% solution)3.5 - 4.5
Particle Size98.5% < 44 ยตm
Zirconiumca. 13.5%
Glycine10.5 - 13.5%
Iron100 ppm max.
Appearancefine powder
Chlorideca. 18%
CAS21645-51-2
FormulaAl(OH)3
SynonymAluminum Hydroxide powder, Aluminum hydroxide (Al(OH)3), Aluminium hydroxide
Density2.42
Na0.5% Max.
As5ppm max.
Heavy Metals50 ppm max.
Ph - stat testmin. 40 ml/ 130 ml/ 270 ml 0.1 n HCI
pH10 Max.
Cl0.85% Max.
Tests ACC. Ph. EuR. II BP 88min. pH 1.8/2.3/3.0 max. 40/ max. 35 ml
Assay50-57.5% Al2O3 min. 76.5% Al(OH)3
Bulk density, loose0.2 - 0.3 g/ml
SO40.6% Max.
Loss on Drying (105ยฐC/ 2h)Approx. 13%
Acid Neutralizing Capacity, USP25 meq/g Min.
Rosett - Rice titrationMin. 30 minutes
Bulk Density, tapped0.3 - 0.4 g/ml
Melting Pointloses water 300 c
Insolubilityin water, alcohol
Odorodorless
Refractive Index1.57
Molecular weight78.01
Solubilitymin. acids, caustic soda
CAS69-72-7
FormulaC7H6O3
Synonym2-Hydroxybenzoic acid, Benzoic acid, 2-hydroxy-, Salicylic acid
Density1.443 (204 c)
Slightly Solublein water, benzene, chloroform
Phenol0.05% Max.
AppearanceWhite Powder Crystal
Melting Point158 - 161C
Chloride0.014% Max.
Sulfate0.02% Max.
Assay99.5% Min.
Heavy Metals0.002% Max.
Water0.5% Max.
Residue on Ignition0.05% Max.
Colordiscolored by light
Molecular weight138.12
Flash Point(tcc) 157 c
Solubilityalcohol, ether, oxygenated and chlorinated solvs.
Boiling Point211 c (20 mm) sublimes at 76 c
CAS309-43-3
FormulaC12H17N2NaO3
SynonymSECOBARBITAL SODIUM SALT, QUINALBARBITONE SODIUM SALT, 5-ALLYL-5-[1-METHYLBUTYL]BARBITURIC ACID SODIUM SALT, 4,6(1h,3h,5h)-pyrimidinetrione,5-(1-methylbutyl)-5-(2-propenyl)-monosodi, 4,6(1h,3h,5h)-pyrimidinetrione,5-(1-methylbutyl)-5-(2-propenyl)-monosodi
EINECS206-218-4
Molecular weight260.26
CAS6055-06-7
FormulaC17H26ClNO6; C17H19NO3.ClH.3H2O
SynonymMorphine hydrochloride trihydrate, 7,8-Didehydro-4,5-alpha-epoxy-17-methylmorphinan-3,6-alpha-diol hydrochloride trihydrate, Morphine HCl hydrate, Morphine hydrochloride trihydrate, UNII-Q5F3AS69LF, Systematic Name Morphinan-3,6-alpha-diol, 7,8-didehydro-
Molecular weight375.84
SMILESO.O.O.Cl.CN1CC[C@]23[C@H]4Oc5c(O)ccc(C[C@@H]1[C@@H]2C=C[C@@H]4O)c35
CAS16893-85-9
FormulaNa2SiF6
SynonymSodium silicofluoride, Sodium hexafluorosilicate, Silicate(2-), hexafluoro-, sodium (1:2), Disodium hexafluorosilicate
Density2.68 kgl
Partly Solublein cold water
Odorodorless
Insolubilityin alcohol
Melting Pointdec. red heat
Molecular weight188.06
CAS66981-73-5
FormulaC21H25N2O4
Synonym7-(3-chloro-6-methyl-6,11-dihydrodibenzo[c,f][1,2]thiazepin-11-ylamino)heptanoic acid S,S-dioxide
Molecular weight436.953
Assay/PurityTypically NLT 98%
CAS58-20-8
FormulaC19H28O2
Synonym(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,1
Molecular weight288.42
Assay/PurityTypically NLT 98%
CAS218949-48-5
FormulaC221H366N72O67S
SynonymTesamorelin, Egrifta, 218949-48-5, TH9507, 804475-66-9, TH 9507, TH-9507, UNII-MQG94M5EEO, Tesamorelin [USAN:INN], MQG94M5EEO, (3E)-hex-3-enoylsomatoliberin, GTPL6959, DTXSID00583207
Assay/PurityTypically NLT 98%
CAS50-65-7
FormulaC13H12N2O5S
Synonym5-chloro-N-(2-chloro-4-nitrophenyl)-2-hydroxybenzamide
Molecular weight327.12
Assay/PurityTypically NLT 98%
CAS79778-41-9
FormulaC6H17NO7P2
Synonym(6-Amino-1-hydroxyhexane-1,1-diyl)bis(phosphonicacid)
Molecular weight277.14
Assay/PurityTypically NLT 98%
CAS130209-82-4
FormulaC26-H40-O5
SynonymIsopropyl (Z)-7-((1R,2R,3R,5S)-3,5-dihydroxy-2-((3R)-3-hydroxy-5-phenylpentyl)cyclopentyl)-5-heptenoate, Latanoprost, PhXA 41, PHXA41, UNII-6Z5B6HVF6O, XA 41, XA41, Xalatan, propan-2-yl (5Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(3R)-3-hydroxy-5-phenylpentyl]cyclopentyl]hept-5-enoate
Molecular weight432.597
Assay/PurityTypically NLT 98%
CAS43210-67-9
FormulaC15H13N3O2S
Synonymmethyl N-(6-phenylsulfanyl-1H-benzoimidazol-2-yl)carbamate
Assay/PurityTypically NLT 98%
CAS147-24-0
FormulaC17H22ClNO
Synonym2-benzhydryloxy-N,N-dimethylethanamine hydrochloride, diphenhydramine hydrochloride
Molecular weight291.8199
Assay/PurityTypically NLT 98%
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